I don’t usually metagame that much. I would much rather play a deck I like and hope its good than try to metagame and play a deck I don’t necessarily like as much and which will cost me a lot of money. However, there’s of course room to metagame within the decks.
Right now, I think one good metagame question is whether you should play Naturalize mainboard.
You should note that Naturalize is used as a generic stand-in for all effects that get rid of enchantments and/or artifacts. These include Unravel the Aether, Revoke Existence and Destructive Revelry.
The real question here is whether there are enough question out there for these to answer. I think, yes.
Looking at the decks I see at my local FNM and on stream when I watch include Monoblack Devotion (sometimes with splash in any other color), Monoblue Devotion, UWx control, Rw Burn, Big Boros, a lot of variants of GR Monsters, Selesnya Aggro, and Jund Monsters. Of course there’s all sorts of brews out there. I myself currently play a Monoblack Aggro. There’s also been a resurgence of hexproof decks, this time in the form of Naya, and Dregde.
What question do these present?
Monoblack Devotion has Underworld Connections, which is kind of a key card for it. The deck is basically a control deck which exchanges cards for cards until it can bury the opponent in card advantage. Also, after boarding, it might have Erebos, God of the Dead.
GR Monsters now has Xenagos, God of the Revels and Courser of Kruphix, which happens to be an enchantment creature. Sometimes they’ll use a Nylea, God of the Hunt to get their big monsters to go over random chump blockers.
My Monoblack Aggro plays Underworld Herald.
The only deck without an enchantment in it is probably the Rw Burn.
So, to me, if you are able to play enchantment removal, do so. It just has so many targets. Removing artifacts is much less important, because the major artifacts used (practically only the weapons) are also enchantments. Since there are plenty of gods out there, I’d rather use Revoke Existence or Unravel the Aether than bb greedy and hope for two damage from Destructive Revelry, although, you can still target the gods and it will still deal the damage even if the target isn’t actually destroyed.